Dave Shiflett, who co-wrote the book, told Refinery29 that, while he didn't think Trump was serious about running for president at the time, he was aware of what an asset Oprah would be were he do so.
Some also halfway joked, or wondered seriously, how Winfrey's speech could launch her bid into politics - or even start her run for president in 2020. I support that as I think everyone should and I think Oprah has a tremendous capacity for human empathy. Her reputation as a performer and influencer and her freedom to say what she wants without risking her career or future prospects were critical factors allowing her to speak. "He would never do that".
And while Winfrey's partner, Stedman Graham, was initially quoted as saying that she "absolutely" would run, he has since said his remarks were taken out of context and that he only meant to convey that she would "absolutely" make a great president if she did run.
Oprah Winfrey is a veteran talk show host and media mogul, with Forbes estimating her net worth at $2.8 billion. "She loves this country and would like to be of service in some way, but I don't think that she's actively considering it".
The possibility of a Winfrey candidacy has energized many Democrats, who view her as the ideal foil to Trump.
Oprah Winfrey delivered a rallying cry to women and hope for "a new day" when receiving the Cecile B. DeMille Award at the 2018 Golden Globes.
As he wrapped up the event, a reporter asked "can you you beat Oprah?"
Let's not forget, her father Donald Trump was infamously caught on tape bragging about sexual assault ("grab them by the pussy") and has been accused of rape and harassment by multiple women. She added that there will come a time when no one else has to say "me too" ever again. "I also know that after years of watching the Oprah show, you always have the right to change your mind".
In the months after the congressional elections, halfway through Trump's four-year term, Democratic presidential challengers are likely to begin announcing their candidacies to run against him.
Stranger Things actress Shannon Purser tweeted: "This is the sermon I needed today".
Tuesday morning's CBS This Morning became a will-she-or-won't-she White House discussion on Winfrey, with co-hosts peppering one of their own with questions, as King has been the queen of talk's longtime best friend.