Team news on the way from Wembley, but how might both sides line up this afternoon?
Cenk Tosun had a forgettable debut for Everton but if he is worth £27million - after scoring goals in Turkey - you have to wonder how much Son is worth. That changed in the 24th minute when Christian Eriksen started the play that led to a goal from Son Heung-Min.
Son, who has had a hand in more goals at Wembley than any other Tottenham player this season with seven goals and four assists, was comfortably the best player on the pitch but it was Kane who assumed centre stage as his 98th top-flight goal arrived in the 59th minute. "His life is probably fantastic at the moment".
But with 26 minutes gone, Son timed everything right when Serge Aurier's scuffed shot fizzed across the box and he steered the ball home from close range.
James Ward-Prowse scored his first two goals of the Premier League season for Southampton but that wasn't enough to give the Saints a desperately-needed win as hosts Watford rallied for a 2-2 draw.
Tottenham are unbeaten in their last 10 Premier League games against Everton (W5 D5), their longest such run against them since a run of 13 between 1997 and 2003.
Kane then drew another save from Pickford before the influential Son came within a whisker of deservedly doubling his personal tally when he collected Kane's crossfield pass, cut inside past two defenders and then fired a low strike against the post with the keeper beaten.
Defensive stability? Yes. Free-flowing, attacking prowess?
Eriksen smashes a thumping drive into the corner to finish off a wonderful move involving Aurier, Son and Alli.
With Tottenham Hotspur playing in Saturday's late kick-off against Everton and runaway leaders Manchester City not facing Liverpool until Sunday, Chelsea were the only top six side involved in a 1500 GMT kick-off.