The Ryan Coogler-directed Marvel hit was the big victor of the night, nabbing four awards including "Best Movie".
The actress said: 'I want you to know how grateful I am to those that support me.
If you're unfamiliar, Roseanne just got her show terminated a couple weeks ago after she sent out some racist tweets about White House aide Valerie Jarrett, saying she looked like a combination of "Muslim brotherhood" and "Planet of the Apes".
His co-star Jordan also won a golden popcorn bucket after being honoured as Best Villain in the film as a U.S. black-ops soldier who seeks to overthrow T'Challa.
The 14-year-old actor appeared via a recorded message to tell her haters off.
In April, a gunman opened fire at a Waffle House, killing four people and wounding several others. She called those documented, many who aren't alive anymore, "the bravest human beings that ever lived". He suffered a graze wound from a bullet and burns on his right hand from grabbing the hot barrel of the gun.
Tiffany Haddish hosted, capping her night with the award for best comedic performance for "Girls Trip" while "Scene Stealer" award went to Madelaine Petsch as Cheryl Blossom in The CW's teen drama series "Riverdale".
In this Saturday, June 16, 2018, photo, Finn Wolfhard, from left, Gaten Matarazzo and Sadie Sink accept the award for best show for "Stranger Things" at the MTV Movie and TV Awards at the Barker Hangar in Santa Monica, Calif.
Stranger Things was named Best TV Show, while Eleven and Mike's dance to Every Breath You Take was named Best Musical Moment.
The nominees are decided by producers and MTV executives, while the winners are chosen by the public, who vote online.